Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291441 | 0.99 | SPHK1 (0.36) | FPR2SPHK1PTPN11 | |
| SCHEMBL9291146 | 0.99 | SPHK1 (0.36) | FPR2SPHK1PTPN11 | |
| SCHEMBL9291460 | 0.99 | SPHK1 (0.36) | FPR2SPHK1PTPN11 | |
| SCHEMBL9291806 | 0.99 | SPHK1 (0.36) | FPR2SPHK1PTPN11 | |
| SCHEMBL9291332 | 0.99 | SPHK1 (0.36) | FPR2SPHK1PTPN11 | |
| SCHEMBL9291245 | 0.98 | PDE4A (0.34) | FPR2SPHK1CYP2C9HRH3PDE4A | |
| SCHEMBL9291443 | 0.94 | FPR2 (0.37) | FPR2PDE4AGABRA1GABRB2KDM4E | |
| SCHEMBL9291266 | 0.90 | KDM1A (0.38) | FPR2CYP2C9PDE4AKDM4EFFAR4 | |
| SCHEMBL19985312 | 0.89 | ESR2 (0.36) | FPR2SPHK1PTPN11CYP2C9HRH3 | |
| SCHEMBL16638902 | 0.88 | SPHK1 (0.37) | FPR2SPHK1PTPN11RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |