SCHEMBL9291355

SCHEMBL9291355

CC(C)(C)c1cc(CCC(=O)NN)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.64
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.47
MAOB P27338 3/20 0.47
MAOA P21397 2/20 0.47
ACHE P22303 1/20 0.45
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.44
AGTR1 P30556 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9501153 0.89 GAA (0.58) GAAKMT2AMEN1MAOBMAOA
SCHEMBL19176292 0.88 GAA (0.45) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9326704 0.88 KMT2A (0.54) GAAKMT2AMEN1MAOBMAOA
SCHEMBL10470076 0.87 GAA (0.47) GAAKMT2AMEN1MAOBMAOA
Hydrochloric Acid SCHEMBL15399357 0.87 KMT2A (0.53) GAAKMT2AMEN1MAOBMAOA
SCHEMBL100766 0.86 MAOB (0.45) GAAKMT2AMEN1MAOBMAOA
SCHEMBL10135977 0.86 GAA (0.44) GAAKMT2AMEN1MAOBMAOA
SCHEMBL29768287 0.86 MAOB (0.45) GAAKMT2AMEN1MAOBMAOA
SCHEMBL8160946 0.86 KMT2A (0.55) GAAKMT2AMEN1MAOBMAOA
SCHEMBL7068865 0.86 GAA (0.47) GAAKMT2AMEN1MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US claimed
EP-0308886-B1 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA (US) 1994-11-23 EP disclosed
US-5319090-A Benzotriazole and oxanilide UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-06-07 US disclosed
US-5233047-A Benzotriazole UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-03 US disclosed
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
EP-0409840-A4 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES 1991-09-04 EP disclosed
US-4980420-A Benzotriazole and oxanilide UV absorber hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1990-12-25 US disclosed
US-4975494-A USING HYDRAZIDE COMPOUND ATOCHEM OF NORTH AMERICA, INC. (US) 1990-12-04 US disclosed
WO-1990009369-A1 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-08-23 WO disclosed
US-4927891-A REACTING LIGHT STABILIZER HYDRAZIDES WITH ACRYLIC RESINS PENNWALT CORPORATION (US) 1990-05-22 US disclosed
US-4874803-A HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY PENNWALT CORPORATION (US) 1989-10-17 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0308886-A2 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-03-29 EP disclosed
EP-0303988-A2 Polymer bound UV stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed