SCHEMBL9501153

SCHEMBL9501153

CC(C)(C)c1cc(CCC(=O)NN)cc(-n2nc3ccc(Cl)cc3n2)c1O

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.58
KMT2A Q03164 3/20 0.44
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.41
MEN1 O00255 2/20 0.40
ACHE P22303 1/20 0.40
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.37
AGTR1 P30556 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
RXFP1 Q9HBX9 1/20 0.36
TP53 P04637 2/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
GSK3B P49841 1/20 0.34
ADORA3 P0DMS8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9291355 0.89 GAA (0.64) GAAKMT2AMAOBMAOAMEN1
SCHEMBL6105535 0.89 GAA (0.48) GAAKMT2AMAOBMAOAMEN1
SCHEMBL29365566 0.88 MAOB (0.40) GAAKMT2AMAOBMAOAMEN1
SCHEMBL13714982 0.88 GAA (0.39) GAAKMT2AMAOBMAOAMEN1
SCHEMBL9870381 0.88 GAA (0.39) GAAKMT2AMAOBMAOAMEN1
SCHEMBL101259 0.88 MAOB (0.40) GAAKMT2AMAOBMAOAMEN1
SCHEMBL10470496 0.88 GAA (0.49) GAAKMT2AMAOBMAOAMEN1
SCHEMBL78795 0.87 GAA (0.42) GAAKMT2AMAOBMAOAMEN1
SCHEMBL29664175 0.87 GAA (0.42) GAAKMT2AMAOBMAOAMEN1
SCHEMBL9501982 0.87 GAA (0.41) GAAALDH1A1LMNASMN1; SMN2RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303988-A2 Polymer bound UV stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed