SCHEMBL10135977

SCHEMBL10135977

CC(=O)CCc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.44
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
MAOB P27338 3/20 0.43
MAOA P21397 2/20 0.43
ACHE P22303 1/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.40
AGTR1 P30556 1/20 0.40
HTT P42858 1/20 0.40
POLB P06746 1/20 0.39
F2R P25116 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29768287 0.91 MAOB (0.45) GAAKMT2AMEN1MAOBMAOA
SCHEMBL100766 0.91 MAOB (0.45) GAAKMT2AMEN1MAOBMAOA
SCHEMBL5566811 0.89 GAA (0.43) GAAKMT2AMEN1MAOBMAOA
SCHEMBL19176292 0.89 GAA (0.45) GAAKMT2AMEN1MAOBMAOA
SCHEMBL9871207 0.89 MAOB (0.44) GAAKMT2AMEN1MAOBMAOA
SCHEMBL13714980 0.89 ALDH1A1 (0.40) GAAKMT2AMEN1MAOBMAOA
SCHEMBL19335916 0.88 GAA (0.43) GAAKMT2AMEN1MAOBMAOA
SCHEMBL31349925 0.88 GAA (0.43) GAAKMT2AMEN1MAOBMAOA
SCHEMBL13714982 0.88 GAA (0.39) GAAKMT2AMEN1MAOBMAOA
Methylene Chloride SCHEMBL23923036 0.87 MAOB (0.43) GAAKMT2AMEN1MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773277-B2 Use of an ultraviolet radiation absorbing polymer composition (UVRAP) as an UV absorbing agent in a coating for non-living and non-keratinous materials BASF SE 2023-10-03 US disclosed
US-11773277-B2 Use of an ultraviolet radiation absorbing polymer composition (UVRAP) as an UV absorbing agent in a coating for non-living and non-keratinous materials BASF SE 2023-10-03 US disclosed
US-11046814-B2 Ultraviolet radiation absorbing polymer composition BASF SE (DE) 2021-06-29 US disclosed
US-20210163710-A1 USE OF AN ULTRAVIOLET RADIATION ABSORBING COMPOSITION AS A LIGHT STABILIZER FOR A SHAPED ARTIFICIAL POLYMER ARTICLE BASF SE (DE) 2021-06-03 US disclosed
US-20210115270-A1 USE OF AN ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION (UVRAP) AS AN UV ABSORBING AGENT IN A COATING FOR NON-LIVING AND NON-KERATINOUS MATERIALS BASF SE (DE) 2021-04-22 US disclosed
EP-3305279-B1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION JOHNSON & JOHNSON CONSUMER INC (US) 2021-04-07 EP disclosed
US-20200299459-A1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION BASF SE (DE) 2020-09-24 US disclosed
US-10647874-B2 Polymer dispersion for durable coating, and the coating comprising the same ROHM AND HAAS COMPANY (US) 2020-05-12 US disclosed
US-10596087-B2 Ultraviolet radiation absorbing polymer composition JOHNSON & JOHNSON CONSUMER INC. (US) 2020-03-24 US disclosed
WO-2019192982-A1 USE OF AN ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION (UVRAP) AS AN UV ABSORBING AGENT IN A COATING FOR NON-LIVING AND NON-KERATINOUS MATERIALS BASF SE (DE) 2019-10-10 WO disclosed
WO-2014004477-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO disclosed
WO-2014004474-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO disclosed
US-20120083497-A1 Method for Combating Harmful Fungi BASF SE (DE) 2012-04-05 US disclosed
US-20120017503-A1 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS BASF SE (DE) 2012-01-26 US disclosed
US-7910642-B2 Stabilization of polyether polyol, polyester polyol or polyurethane compositions BASF SE (DE) 2011-03-22 US disclosed
US-20090306256-A1 Styrene butadiene styrene block copolymer based adhesive compositions with improved photo-oxidation resistance CIBA SPECIALTY CHEMICALS CORP. 2009-12-10 US disclosed
US-20090306256-A1 Styrene butadiene styrene block copolymer based adhesive compositions with improved photo-oxidation resistance CIBA SPECIALTY CHEMICALS CORP. 2009-12-10 US disclosed
US-7572843-B2 ink jets; colorfastness CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-08-11 US disclosed
EP-1885814-B1 STYRENE BUTADIENE STYRENE BLOCK COPOLYMER BASED ADHESIVE COMPOSITIONS WITH IMPROVED PHOTO-OXIDATION RESISTANCE CIBA HOLDING INC (CH) 2009-05-27 EP disclosed
EP-1765928-B1 STABILIZATION OF POLYETHER POLYOL, POLYESTER POLYOL OR POLYURETHANE COMPOSITIONS CIBA HOLDING INC (CH) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299459-A1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION GGCT, UGT1A3, B3GAT3 GAA 255/4885KMT2A 3299/4885MEN1 2310/4885
US-20120017503-A1 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS UNG, ERCC5, ERCC4 GAA 130/4885KMT2A 3578/4885MEN1 4540/4885
US-11046814-B2 Ultraviolet radiation absorbing polymer composition GGCT, B3GAT3, UGT1A3 GAA 167/4885KMT2A 3636/4885MEN1 2318/4885
US-20120083497-A1 Method for Combating Harmful Fungi BROX, CRY1, GUSB GAA 105/4885KMT2A 2802/4885MEN1 1512/4885
US-10596087-B2 Ultraviolet radiation absorbing polymer composition ERCC4, ERCC5, ERCC1 GAA 2391/4885KMT2A 4518/4885MEN1 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.