SCHEMBL9291385

SCHEMBL9291385

Cc1cc(-c2ccccc2C[S])cc(C(C)(C)C)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 4/20 0.56
CYP2C19 P33261 4/20 0.56
CYP1A2 P05177 2/20 0.56
PTPN1 P18031 1/20 0.41
CA2 P00918 3/20 0.41
CA1 P00915 1/20 0.41
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
HSPA5 P11021 1/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
HIF1A Q16665 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP2D6 P10635 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
TYR P14679 1/20 0.36
PTGS1 P23219 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29015802 0.85 CYP1A2 (0.71) CYP2C9CYP2C19CYP1A2PTPN1CA2
SCHEMBL9786069 0.76 CA2 (0.50) CYP2C9CYP2C19CYP1A2PTPN1CA2
SCHEMBL13840639 0.75 CYP1A2 (0.78) CYP2C9CYP2C19CYP1A2PTPN1CA2
SCHEMBL11427045 0.75 CA2 (0.57) CYP2C9CYP2C19CYP1A2PTPN1CA2
SCHEMBL8772437 0.75 CYP1A2 (0.61) CYP2C9CYP2C19CYP1A2PTPN1CA2
SCHEMBL31006760 0.74 CA2 (0.67) CYP2C9CYP2C19CYP1A2PTPN1CA2
SCHEMBL2343165 0.74 CYP2C9 (1.00) CYP2C9CYP2C19CYP1A2CA2CA1
SCHEMBL9172068 0.74 GAA (0.48) PTPN1CA2CA1HSPA5MEN1
SCHEMBL10867354 0.74 HSPA5 (0.54) CYP2C9CYP2C19CYP1A2PTPN1CA2
SCHEMBL29489568 0.73 PTGER4 (0.57) PTPN1CA2CA1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5352719-A Blended with synthetic or natural polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-10-04 US disclosed
US-5319090-A Benzotriazole and oxanilide UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-06-07 US disclosed
US-5233047-A Benzotriazole UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-03 US disclosed
US-5116976-A HINDERED AMINE LIGHT STABILIZER HYDRAZIDES ATOCHEM NORTH AMERICA, INC (US) 1992-05-26 US disclosed
EP-0467344-A1 Hindered amine light stabilizer hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-01-22 EP disclosed
EP-0409840-A4 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES 1991-09-04 EP disclosed
US-5041545-A 2-hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1991-08-20 US disclosed
EP-0409840-A1 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-01-30 EP disclosed
US-4980420-A Benzotriazole and oxanilide UV absorber hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1990-12-25 US disclosed
WO-1990009369-A1 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-08-23 WO disclosed