Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529272 | 0.88 | CYP2C9 (0.47) | CYP3A4CYP2D6CYP2C9ALDH1A1HPGD | |
| SCHEMBL3000531 | 0.88 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1HPGD | |
| SCHEMBL1876189 | 0.83 | SMN1; SMN2 (0.48) | CYP3A4CYP2D6CYP2C9ALDH1A1HPGD | |
| SCHEMBL11862057 | 0.80 | CYP3A4 (0.56) | CYP3A4CYP2D6CYP2C9ALDH1A1HPGD | |
| SCHEMBL15095589 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EMAPTALOX15 | |
| SCHEMBL11509995 | 0.78 | KMT2A (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1MAPT | |
| SCHEMBL11312625 | 0.78 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP2C9ALDH1A1HPGD | |
| SCHEMBL11873979 | 0.77 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1KDM4E | |
| SCHEMBL8991513 | 0.77 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1HPGD | |
| SCHEMBL9656596 | 0.77 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5247009-A | Reacted with an imine and an acid halide, tires | NIPPON ZEON CO., LTD. (JP) | 1993-09-21 | — | — | US | claimed |
| US-5312849-A | Modified diene polymer, carbon black | NIPPON ZEON CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5247009-A | Reacted with an imine and an acid halide, tires | NIPPON ZEON CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0087963-B1 | PHTHALONITRILE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Hitachi, Ltd. (JP) | 1989-05-03 | — | — | EP | disclosed |
| EP-0198294-B1 | METHOD FOR MODIFYING RUBBERS | NIPPON ZEON CO., LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |
| US-4677153-A | REACTING WITH AN ACYL HALIDE AND | NIPPON ZEON CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0198294-A1 | Method for modifying rubbers | NIPPON ZEON CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |
| US-4479885-A | Phthalonitrile derivatives and a liquid crystal composition containing the same | HITACHI, LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| US-4279770-A | Liquid crystal 2,3-dicyano-hydroquinone derivatives | CHISSO CORPORATION (JP) | 1981-07-21 | — | — | US | disclosed |