Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MPI | P34949 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862057 | 0.90 | CYP3A4 (0.56) | CYP3A4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL8991513 | 0.78 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL3000531 | 0.78 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9ALDH1A1KDM4E | |
| SCHEMBL11873979 | 0.78 | CYP3A4 (0.52) | CYP3A4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL12660537 | 0.77 | CYP3A4 (0.41) | CYP3A4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL9292208 | 0.77 | CYP3A4 (0.51) | CYP3A4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL11810613 | 0.77 | CYP3A4 (0.51) | CYP3A4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL7644622 | 0.76 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL21765629 | 0.75 | CYP3A4 (0.68) | CYP3A4CYP2D6CYP2C9MAPTKDM4E | |
| SCHEMBL9358818 | 0.74 | CYP3A4 (0.48) | CYP3A4CYP2D6CYP2C9CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151333-A | Containing imine derivative | NIPPON ZEON CO., LTD (JP) | 1992-09-29 | — | — | US | disclosed |