SCHEMBL929237

SCHEMBL929237

C(#Cc1ccccc1)Nc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.52
MAPT P10636 3/20 0.41
PTPN11 Q06124 1/20 0.40
CYP1A2 P05177 3/20 0.39
CYP3A4 P08684 3/20 0.39
CYP2C9 P11712 3/20 0.39
CYP2C19 P33261 3/20 0.39
THPO P40225 1/20 0.39
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
CTSD P07339 1/20 0.39
GRM5 P41594 2/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
MAPK1 P28482 2/20 0.38
MEN1 O00255 2/20 0.38
HPGD P15428 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429053 0.95 APP (0.55) APPMAPTPTPN11CYP1A2CYP3A4
SCHEMBL28548217 0.85 APP (0.42) APPMAPTCYP1A2CYP3A4CYP2C9
SCHEMBL28649524 0.85 MAPT (0.59) APPMAPTCYP1A2CYP3A4CYP2C9
SCHEMBL29000005 0.85 TSHR (0.50) APPMAPTALDH1A1MEN1KMT2A
SCHEMBL28549450 0.85 HPGD (0.48) APPMAPTALDH1A1TDP1GRM5
SCHEMBL28649522 0.85 MAPT (0.59) APPMAPTCYP1A2CYP3A4CYP2C9
SCHEMBL31026477 0.82 APP (0.34) APPMAPTPTPN11CYP1A2CYP3A4
SCHEMBL1922270 0.81 ALDH1A1 (0.50) MAPTCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL3840989 0.80 CYP2A6 (0.49) CYP1A2CYP3A4CYP2C9CYP2C19GRM5
SCHEMBL31026514 0.80 NPSR1 (0.48) MAPTPTPN11CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057623-B N-naphthyl indole derivative and synthesis method thereof 湖南第一师范学院 2023-07-21 CN claimed
CN-114057623-A N-naphthyl indole derivative and synthetic method thereof 湖南第一师范学院 2022-02-18 CN claimed
CN-114031613-A 1- (benzo [ b ] thiophene-7-yl) -indole derivative and synthetic method thereof 湖南第一师范学院 2022-02-11 CN claimed
US-20110003955-A1 Imide Oligomer And Polyimide Resin Obtained By Thermal Curing Thereof DAIWA CAN COMPANY (JP) 2011-01-06 US claimed
EP-2246383-A1 IMIDE OLIGOMER AND POLYIMIDE RESIN OBTAINED BY THERMAL CURING THEREOF DAIWA CAN COMPANY (JP) 2010-11-03 EP claimed
US-7019103-B2 Polyamic acid oligomer, polyimide oligomer, solution composition, and fiber-reinforced composite material JSR CORPORATION (JP) 2006-03-28 US claimed
US-20050014925-A1 Polyamic acid oligomer, polyimide oligomer, solution composition, and fiber-reinforced composite material JSR CORPORATION (JP) 2005-01-20 US claimed
US-5478913-A Copolymerizing biphenyl dianhydride as ester/acid/ with mix of m- or p-phenylenediamines and aminophenoxybenzene component encapped with phthalic anhydride or ethynyl-group amine or anhydride; heat, oxidation resistant; prepregs E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-26 US claimed
JP-7238069-A None JP disclosed
CN-119264028-A 1-Trifluoromethylthio-indole Synthesis method of indole compound 江南大学 2025-01-07 CN disclosed
CN-118530235-A Method for synthesizing indolo [1,2-f ] phenanthridine compound by micelle catalytic decarboxylation coupling cyclization aqueous phase 新乡市润宇新材料科技有限公司 2024-08-23 CN disclosed
CN-118388460-A 5- (1H-indole-1-yl) -dihydrofuran-2- (3H) -ketone compound and synthetic method thereof 华南理工大学 2024-07-26 CN disclosed
CN-115028568-B Synthesis method of 3-selenoindole compound promoted by visible light 南通大学 2023-12-19 CN disclosed
CN-114230792-B Positive photosensitive polyimide resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-10-03 CN disclosed
EP-0493650-A1 Fluorinated acetylene-containing aromatic amines and diamines National Starch and Chemical Investment Holding Corporation (US) 1992-07-08 EP disclosed
EP-0493650-A1 Fluorinated acetylene-containing aromatic amines and diamines National Starch and Chemical Investment Holding Corporation (US) 1992-07-08 EP disclosed
US-5107026-A Fluorinated acetylene-containing aromatic amines and diamines NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1992-04-21 US disclosed
US-5107026-A Fluorinated acetylene-containing aromatic amines and diamines NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1992-04-21 US disclosed
EP-0279921-A2 Phenylacetylene-substituted schiff's base momomers and electroconductive polymers National Starch and Chemical Investment Holding Corporation (US) 1988-08-31 EP disclosed
US-4730032-A MOLDING MATERIALS NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1988-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003955-A1 Imide Oligomer And Polyimide Resin Obtained By Thermal Curing Thereof PUF60, SMARCC2, SMARCA4 APP 3433/4885MAPT 1429/4885PTPN11 3094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.