Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929237 | 0.85 | APP (0.52) | APPKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL29429053 | 0.81 | APP (0.55) | APPKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28649524 | 0.80 | MAPT (0.59) | APPKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28549450 | 0.80 | HPGD (0.48) | APPKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28953063 | 0.76 | NPC1 (0.56) | APPKMT2ANPC1RAB9AGFER | |
| SCHEMBL6117721 | 0.75 | MAPT (0.44) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL717468 | 0.75 | APP (0.67) | APPKMT2ANPC1MEN1MAPT | |
| SCHEMBL18867945 | 0.75 | APP (0.67) | APPKMT2ANPC1MEN1MAPT | |
| SCHEMBL28797622 | 0.73 | ALDH1A1 (0.50) | APPKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28649522 | 0.72 | MAPT (0.59) | APPKMT2ANPC1RAB9AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552242-B | Method for synthesizing cinnoline salt compound | 温州大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-112552242-A | Method for synthesizing cinnoline salt compound | 温州大学 | 2021-03-26 | — | — | CN | disclosed |