SCHEMBL9292891

SCHEMBL9292891

Cc1cc(C)n(-c2cccc(S(N)(=O)=O)c2)n1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.54
CA1 P00915 6/20 0.50
CA2 P00918 6/20 0.50
CA9 Q16790 4/20 0.50
F10 P00742 1/20 0.50
PTGS2 P35354 1/20 0.50
TERT O14746 1/20 0.48
CA12 O43570 2/20 0.48
LMNA P02545 2/20 0.48
NAMPT P43490 2/20 0.45
ALDH1A1 P00352 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CA7 P43166 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18717609 0.87 ALDH1A1 (0.63) CA1CA2CA9F10PTGS2
SCHEMBL28060810 0.87 F10 (0.52) HTTCA1CA2CA9F10
SCHEMBL12395128 0.85 SMN1; SMN2 (0.53) HTTTERTLMNANAMPTALDH1A1
SCHEMBL5698738 0.83 PTGS2 (0.65) HTTCA1CA2CA9PTGS2
SCHEMBL1075204 0.76 ALDH1A1 (0.56) HTTTERTALDH1A1SMN1; SMN2
SCHEMBL29448492 0.76 ALDH1A1 (0.56) HTTTERTALDH1A1SMN1; SMN2
SCHEMBL18055499 0.76 MAPT (0.64) HTTLMNAALDH1A1SMN1; SMN2
SCHEMBL9198386 0.76 CA1 (0.55) CA1CA2CA9CA12LMNA
SCHEMBL8338087 0.75 ALDH1A1 (0.69) HTTLMNAALDH1A1SMN1; SMN2
SCHEMBL11698430 0.75 ALDH1A1 (0.63) PTGS2LMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0382436-A1 N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP claimed
US-5362885-A Herbicides KUREHA KAGAKU KOGYO K.K. (JP) 1994-11-08 US disclosed
US-5242894-A N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, and herbicidal compositions KUREHA KAGAKU KOGYO K.K. (JP) 1993-09-07 US disclosed
US-5127937-A N-SUBSTITUTED-3-(NITROGEN-CONTAINING 5-MEMBERED RING)-BENZENESULFONAMIDE DERIVATIVES, AND HERBICIDAL COMPOSITIONS KUREHA KAGAKU KOGYO K.K. (JP) 1992-07-07 US disclosed
EP-0382436-A1 N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP disclosed