Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 4/20 | 0.75 |
| ▸ | CCKBR | P32239 | 4/20 | 0.75 |
| ▸ | SCN9A | Q15858 | 16/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292830 | 1.00 | CCKAR (0.75) | CCKARCCKBRSCN9A | |
| SCHEMBL9122887 | 0.89 | CCKBR (0.71) | CCKARCCKBRSCN9A | |
| SCHEMBL9124084 | 0.89 | CCKBR (0.71) | CCKARCCKBRSCN9A | |
| SCHEMBL9868387 | 0.86 | CCKBR (1.00) | CCKARCCKBRSCN9A | |
| SCHEMBL9866835 | 0.86 | CCKBR (1.00) | CCKARCCKBRSCN9A | |
| SCHEMBL9292409 | 0.84 | CCKBR (0.58) | CCKARCCKBRSCN9A | |
| SCHEMBL9292874 | 0.84 | CCKBR (0.58) | CCKARCCKBRSCN9A | |
| SCHEMBL9121125 | 0.82 | SCN9A (0.69) | CCKARCCKBRSCN9A | |
| SCHEMBL9122014 | 0.82 | SCN9A (0.69) | CCKARCCKBRSCN9A | |
| SCHEMBL8746581 | 0.81 | CCKBR (0.80) | CCKARCCKBRSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322842-A | Tricyclic benzodiazepine derivates, their preparation, and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0544909-A1 | TRICYCLIC BENZODIAZEPINE DERIVATES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003438-A1 | TRICYCLIC BENZODIAZEPINE DERIVATES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-05 | — | — | WO | disclosed |