SCHEMBL9293147

SCHEMBL9293147

COCCNC(=O)CC[O]

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
CNR1 P21554 1/20 0.49
HPGD P15428 7/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
KDM4E B2RXH2 3/20 0.46
GLA P06280 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.42
CYP2C19 P33261 2/20 0.41
POLB P06746 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23478140 0.89 TSHR (0.65) TSHRCNR1HPGDSMN1; SMN2HTT
SCHEMBL10496 0.83 TSHR (0.59) TSHRCNR1HPGDSMN1; SMN2HTT
SCHEMBL3927116 0.83 TSHR (0.59) TSHRCNR1HPGDSMN1; SMN2HTT
SCHEMBL23729602 0.83 TSHR (0.77) TSHRCNR1HPGDSMN1; SMN2HTT
SCHEMBL1569761 0.83 TSHR (0.59) TSHRCNR1HPGDSMN1; SMN2HTT
SCHEMBL4814439 0.82
SCHEMBL13581470 0.81 TSHR (0.57) TSHRCNR1HPGDSMN1; SMN2HTT
SCHEMBL16181342 0.81 TSHR (0.57) TSHRCNR1HPGDSMN1; SMN2HTT
SCHEMBL14271590 0.81 TSHR (0.57) TSHRCNR1HPGDSMN1; SMN2HTT
SCHEMBL40921 0.81 TSHR (0.57) TSHRCNR1HPGDSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0500043-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1994-05-04 EP disclosed
US-5302503-A Sulfonylurea-containing coupler for color films; high dye forming rate and color forming density; sharpness; sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1994-04-12 US disclosed
EP-0500043-A1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1992-08-26 EP disclosed
US-5077182-A Cyan/magenta/yellow couplers having specific spectral sensitometric properties; negative interlayer effect; color reproduction; graininess; image sharpness FUJI PHOTO FILM CO., LTD. (JP) 1991-12-31 US disclosed
US-5049474-A Color light-sensitive material FUJI PHOTO FILM CO., LTD (JP) 1991-09-17 US disclosed
EP-0281118-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-04-10 EP disclosed
US-4886736-A COUPLERS AND COMPOUND CAPABLE OF RELEASING PHOTOGRAPHICALLY USEFUL GROUP UPON REDUCTION FUJI PHOTO FILM CO., LTD. (JP) 1989-12-12 US disclosed
US-4814261-A Silver halide photographic material containing a development restrainer or a precursor thereof FUJI PHOTO FILM CO., LTD. (JP) 1989-03-21 US disclosed
EP-0281118-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-09-07 EP disclosed