Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.48 |
| ▸ | USP7 | Q93009 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29485631 | 0.86 | ESR1 (0.50) | ESR1USP7ESR2MAPK1KDM4E | |
| SCHEMBL28643444 | 0.86 | ESR1 (0.50) | ESR1USP7ESR2MAPK1KDM4E | |
| SCHEMBL947755 | 0.84 | ESR1 (0.49) | ESR1USP7ESR2MAPK1KDM4E | |
| SCHEMBL3231646 | 0.83 | ALOX5 (0.42) | ESR1ESR2TP53CNR1CNR2 | |
| SCHEMBL28638714 | 0.79 | MAPK1 (0.43) | ESR1USP7MAPK1KDM4ELMNA | |
| SCHEMBL29485643 | 0.79 | MAPK1 (0.43) | ESR1USP7MAPK1KDM4ELMNA | |
| SCHEMBL5274700 | 0.78 | ESR1 (0.53) | ESR1USP7ESR2MAPK1KDM4E | |
| Propane SCHEMBL10488473 | 0.78 | ESR1 (0.44) | ESR1USP7ESR2ALOX5SENP1 | |
| SCHEMBL3215348 | 0.78 | TYR (0.42) | ESR2MAPK1KDM4EKMT2ANPSR1 | |
| SCHEMBL28519714 | 0.77 | USP7 (0.51) | ESR1USP7ESR2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34626-E | Isomerization of bisphenols | BAYER AG (DE) | 1994-05-31 | — | — | US | disclosed |
| US-5015784-A | Isomerization catalysts of acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |