SCHEMBL9293183

SCHEMBL9293183

Cc1ccc(S(=O)(=O)OCC(F)(F)C(F)(F)C(F)(F)CO)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 2/20 0.42
CTDSP1 Q9GZU7 1/20 0.38
SIRT5 Q9NXA8 1/20 0.38
ALDH1A1 P00352 5/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2D6 P10635 1/20 0.35
GAA P10253 2/20 0.35
BCHE P06276 2/20 0.35
ACHE P22303 2/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23882170 0.96 STAT3 (0.39) STAT3CTDSP1SIRT5ALDH1A1MEN1
SCHEMBL23882162 0.91 STAT3 (0.41) STAT3CTDSP1SIRT5ALDH1A1MEN1
SCHEMBL19436459 0.86 GAA (0.43) STAT3ALDH1A1MEN1KMT2ACYP2D6
SCHEMBL4335889 0.84 CA2 (0.39) STAT3ALDH1A1MEN1KMT2ACYP2D6
SCHEMBL19476713 0.83 ALDH1A1 (0.44) STAT3CTDSP1SIRT5ALDH1A1MEN1
SCHEMBL16930312 0.83 STAT3 (0.42) STAT3CTDSP1SIRT5ALDH1A1MEN1
SCHEMBL2533175 0.83 GAA (0.41) STAT3ALDH1A1MEN1KMT2ACYP2D6
SCHEMBL28268959 0.81 ALDH1A1 (0.41) STAT3ALDH1A1MEN1KMT2ACYP2D6
SCHEMBL30417836 0.81 CYP2C19 (0.39) STAT3CTDSP1SIRT5ALDH1A1MEN1
SCHEMBL14353045 0.80 ALDH1A1 (0.44) STAT3CTDSP1SIRT5ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5298083-A Exposure of substrate to solvent ALLIEDSIGNAL INC. (US) 1994-03-29 US disclosed
US-5275669-A Degreasing glass, metal, plastic and fiber surfaces ALLIEDSIGNAL INC. (US) 1994-01-04 US disclosed