Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850809 | 0.77 | KDM4E (0.50) | TSHRCYP3A4HSD17B10LMNAKDM4E | |
| SCHEMBL1515929 | 0.77 | TSHR (0.59) | TSHRCYP3A4HSD17B10LMNAMAPK1 | |
| SCHEMBL4410404 | 0.76 | TSHR (0.47) | TSHRCYP3A4HSD17B10LMNANPC1 | |
| SCHEMBL11516666 | 0.73 | L3MBTL1 (0.52) | LMNANPC1KDM4EGLAL3MBTL1 | |
| SCHEMBL21939126 | 0.73 | KDM4E (0.45) | TSHRCYP3A4HSD17B10LMNAKDM4E | |
| SCHEMBL1880513 | 0.73 | ALDH1A1 (0.56) | TSHRCYP3A4HSD17B10LMNAKDM4E | |
| SCHEMBL20504933 | 0.73 | TSHR (0.49) | TSHRHSD17B10LMNATHRBKDM4E | |
| SCHEMBL21939119 | 0.71 | TSHR (0.53) | TSHRCYP3A4HSD17B10LMNANPC1 | |
| SCHEMBL1672245 | 0.71 | CA12 (0.61) | TSHRHSD17B10LMNAGLAL3MBTL1 | |
| SCHEMBL7802436 | 0.70 | TSHR (0.76) | TSHRCYP3A4HSD17B10LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34524-E | High glass transition temperature | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0338674-B1 | POLYIMIDE COATING COMPOSITIONS BASED ON META-DIALKYDIHYDROGEN PYROMELLITATE AND AROMATIC DIAMINES | International Business Machines Corporation (US) | 1993-06-09 | — | — | EP | disclosed |
| EP-0338674-A1 | Polyimide coating compositions based on meta-dialkydihydrogen pyromellitate and aromatic diamines | International Business Machines Corporation (US) | 1989-10-25 | — | — | EP | disclosed |
| US-4849501-A | Polyimide coating compositions based on meta-dialkyldihydrogen pyromellitate and aromatic diamines | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1989-07-18 | — | — | US | disclosed |