Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 1.00 |
| ▸ | RAB9A | P51151 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | PKM | P14618 | 5/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.64 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848768 | 0.88 | NPC1 (0.78) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL13325926 | 0.87 | RAB9A (0.77) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL13325909 | 0.87 | RAB9A (0.83) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL13325938 | 0.85 | RAB9A (0.80) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL12797442 | 0.84 | RAB9A (0.73) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL13325732 | 0.84 | RAB9A (1.00) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL6389098 | 0.84 | KDM4E (0.72) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL1494815 | 0.83 | KDM4E (0.74) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL6388717 | 0.82 | RAB9A (0.71) | NPC1RAB9AKDM4EPKMEPHX2 | |
| SCHEMBL13325773 | 0.82 | ALDH1A3 (1.00) | NPC1RAB9AKDM4EPKMEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812530-A | Method for preparing imidazole pyridine compound by catalyzing lignin and model compound by Pd/C bi-component system | 中国科学院大连化学物理研究所 | 2024-10-22 | — | — | CN | claimed |
| CN-115043837-B | Synthesis method and application of 4-imidazo-pyridinyl-thio-isoquinoline heterocyclic compound | 河南工业大学 | 2024-02-20 | — | — | CN | claimed |
| CN-115043837-A | Synthesis method and application of 4-imidazopyridinylthioisoquinoline heterocyclic compound | 河南工业大学 | 2022-09-13 | — | — | CN | claimed |
| CN-118852157-A | Preparation method and application of imidazopyridine compound | 南昌大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-118812530-A | Method for preparing imidazole pyridine compound by catalyzing lignin and model compound by Pd/C bi-component system | 中国科学院大连化学物理研究所 | 2024-10-22 | — | — | CN | disclosed |
| EP-3962915-B1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2024-09-04 | — | — | EP | disclosed |
| CN-115043837-B | Synthesis method and application of 4-imidazo-pyridinyl-thio-isoquinoline heterocyclic compound | 河南工业大学 | 2024-02-20 | — | — | CN | disclosed |
| WO-2023142128-A1 | METHOD FOR SYNTHESIZING 2-PHENYL-5-BENZYL-IMIDAZO[1,2-A]PYRIDINE COMPOUND | 苏州大学 | 2023-08-03 | — | — | WO | disclosed |
| CN-115043837-A | Synthesis method and application of 4-imidazopyridinylthioisoquinoline heterocyclic compound | 河南工业大学 | 2022-09-13 | — | — | CN | disclosed |
| US-20220185822-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2022-06-16 | — | — | US | disclosed |
| US-20220185822-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2022-06-16 | — | — | US | disclosed |
| EP-0411754-A2 | Medicament for the inhibition of interleukin-1 or tumor necrosis factor production by monocytes and/or macrophages | SMITHKLINE BEECHAM CORPORATION (US) | 1991-02-06 | — | — | EP | disclosed |
| WO-1991000092-A1 | INHIBITION OF INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR PRODUCTION BY MONOCYTES AND/OR MACROPHAGES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-01-10 | — | — | WO | disclosed |
| US-4242513-A | CHROMOGENS; PRESSURE AND HEAT SENSITIVE MARKING | APPLETON PAPERS INC. (US) | 1980-12-30 | — | — | US | disclosed |
| US-4163745-A | ANTIDIABETIC, HYPOGLYCEMIC | PFIZER INC. (US) | 1979-08-07 | — | — | US | disclosed |
| US-4141898-A | Imidazo pyridinium quaternary salts as hypoglycemic agents | PFIZER INC. (US) | 1979-02-27 | — | — | US | disclosed |
| US-4129567-A | IMIDAZOPYRIDINES AND ISOB IDINE | PFIZER INC. (US) | 1978-12-12 | — | — | US | disclosed |
| US-4097598-A | Quaternary salts as hypoglycemic agents | PFIZER INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4093616-A | PYRROLO(1,2-A)PYRAZINIUM, PYRAZOLO(1,5-A)PYRIDINIUM, 1H-IMIDAZO(2,1-A)ISOQUINOLINIUM, OR IMIDAZO(5,1-A)ISOQUINOLINIUM SALTS | PFIZER INC. (US) | 1978-06-06 | — | — | US | disclosed |
| US-4044015-A | Imidazopyridinium compounds as hypoglycemic agents | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185822-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | NR1I2, NR1H2, NR1H4 | NPC1 366/4885RAB9A 4268/4885KDM4E 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.