Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294218 | 1.00 | NPC1 (0.57) | NPC1RECQLRAB9ASMN1; SMN2NAAA | |
| SCHEMBL4921596 | 0.98 | NPC1 (0.59) | NPC1RECQLRAB9ASMN1; SMN2NAAA | |
| SCHEMBL4920810 | 0.94 | SMN1; SMN2 (0.65) | NPC1RECQLRAB9ASMN1; SMN2NAAA | |
| SCHEMBL4910834 | 0.87 | MGLL (0.52) | NPC1RECQLRAB9ASMN1; SMN2LMNA | |
| SCHEMBL8924878 | 0.87 | CHRNB2 (0.55) | NPC1RECQLRAB9ASMN1; SMN2NAAA | |
| SCHEMBL4919043 | 0.87 | SMN1; SMN2 (0.56) | NPC1RECQLRAB9ASMN1; SMN2NAAA | |
| SCHEMBL8923767 | 0.86 | CHRNB2 (0.54) | NPC1RECQLRAB9ASMN1; SMN2NAAA | |
| SCHEMBL4920505 | 0.85 | CHRNB2 (0.56) | NPC1RECQLRAB9ASMN1; SMN2NAAA | |
| SCHEMBL5213750 | 0.83 | NPC1 (0.59) | NPC1RECQLRAB9ASMN1; SMN2NAAA | |
| SCHEMBL7771581 | 0.82 | NPC1 (0.55) | NPC1RECQLRAB9ASMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |