Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | MITF | O75030 | 2/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 6/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294171 | 1.00 | CREBBP (0.55) | CREBBPNPC1RAB9ASMN1; SMN2NR1H4 | |
| SCHEMBL9293883 | 0.88 | HIF1A (0.61) | CREBBPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9293885 | 0.88 | HIF1A (0.61) | CREBBPNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12455934 | 0.84 | EGFR (0.54) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL94198 | 0.84 | EGFR (0.54) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL19501547 | 0.84 | LPAR1 (0.51) | CREBBPNPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL27258987 | 0.83 | MMP1 (0.58) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2428674 | 0.82 | MAOB (0.57) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7273555 | 0.82 | MAOB (0.57) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1439557 | 0.82 | TRPV1 (0.48) | CREBBPNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |