Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501010 | 0.93 | EGFR (0.52) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL94198 | 0.90 | EGFR (0.54) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL12455934 | 0.90 | EGFR (0.54) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL19501828 | 0.86 | KMT2A (0.49) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL9294171 | 0.84 | CREBBP (0.55) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9294166 | 0.84 | CREBBP (0.55) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27258987 | 0.83 | MMP1 (0.58) | LPAR1LPAR2MAPTKMT2AMEN1 | |
| SCHEMBL12246139 | 0.82 | MAOB (0.57) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL7273562 | 0.82 | MAOB (0.57) | LPAR1LPAR2MAPTKMT2AMEN1 | |
| SCHEMBL7273555 | 0.82 | MAOB (0.57) | LPAR1LPAR2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343438-B2 | Heat-sensitive recording material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-07-09 | — | — | US | disclosed |
| US-20170297355-A1 | Heat-Sensitive Recording Material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170297355-A1 | Heat-Sensitive Recording Material | SCN1A, SCN3A, KCNN3 | LPAR1 4014/4885LPAR2 4038/4885MAPT 796/4885 |
| US-10343438-B2 | Heat-sensitive recording material | SCN1A, SCN3A, KCNN3 | LPAR1 4014/4885LPAR2 4038/4885MAPT 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.