Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345479 | 0.89 | KCNQ2 (0.45) | KCNQ2MAPTKMT2AHTTL3MBTL1 | |
| SCHEMBL20520340 | 0.89 | PPARG (0.49) | KCNQ2MAPTKMT2AHTTL3MBTL1 | |
| SCHEMBL8366593 | 0.86 | KMT2A (0.46) | KCNQ2MAPTKMT2AHTTL3MBTL1 | |
| SCHEMBL2393158 | 0.85 | AKR1C3 (0.48) | KCNQ2MAPTHTTAKR1C3AKR1C2 | |
| SCHEMBL11069820 | 0.83 | SOAT1 (0.44) | KCNQ2MAPTKMT2APPARAPPARG | |
| SCHEMBL29418186 | 0.82 | SOAT1 (0.47) | KCNQ2MAPTKMT2APPARAPPARG | |
| SCHEMBL11109504 | 0.81 | KMT2A (0.49) | KCNQ2MAPTKMT2AL3MBTL1PPARA | |
| SCHEMBL13465547 | 0.81 | KMT2A (0.45) | KCNQ2MAPTKMT2APPARAPPARG | |
| SCHEMBL2395284 | 0.81 | AKR1C3 (0.46) | KCNQ2MAPTKMT2APPARAPPARG | |
| SCHEMBL29154198 | 0.81 | ALDH1A1 (0.43) | KCNQ2MAPTKMT2AL3MBTL1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326495-A | Tetrasubstituted methanes having liquid-crystalline properties | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-07-05 | — | — | US | disclosed |
| US-5045336-A | Reducing sweet taste of high sugar foods, organic acids and acid salts | AMSTAR SUGAR CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0159864-B1 | METHOD OF MODIFYING TASTE | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1989-07-19 | — | — | EP | disclosed |
| EP-0159864-A2 | Method of modifying taste | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1985-10-30 | — | — | EP | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |