Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418186 | 0.95 | SOAT1 (0.47) | SOAT1KMT2AMAPTKCNQ2PPARA | |
| SCHEMBL8366593 | 0.90 | KMT2A (0.46) | SOAT1KMT2AMAPTKCNQ2PPARA | |
| SCHEMBL5694338 | 0.87 | KMT2A (0.46) | KMT2AMAPTKCNQ2PPARAPPARG | |
| SCHEMBL11242992 | 0.86 | DRD3 (0.45) | SOAT1KMT2AMAPTKCNQ2KDM4E | |
| SCHEMBL11254982 | 0.86 | SCN1A (0.42) | SOAT1KMT2AMAPTKCNQ2MEN1 | |
| SCHEMBL248246 | 0.84 | KMT2A (0.44) | KMT2AMAPTPPARGKDM4EALDH1A1 | |
| SCHEMBL11261260 | 0.83 | KDM4E (0.50) | KMT2AKDM4EALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9294341 | 0.83 | KCNQ2 (0.53) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL27520955 | 0.83 | CYSLTR2 (0.45) | KMT2AMMEMAPTPPARAPPARG | |
| SCHEMBL10976123 | 0.82 | CNR2 (0.42) | KMT2AMMEMAPTPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453005-A | Process for preparing substituted phenylalkenoic acids | MERCK FROSST CANADA, INC. (CA) | 1984-06-05 | — | — | US | disclosed |