Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.59 |
| ▸ | PDE4A | P27815 | 12/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815371 | 0.92 | ADORA2A (0.51) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9294204 | 0.91 | ADORA2A (0.50) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9293917 | 0.89 | ADORA2B (0.66) | ADORA2AADORA2BMAPK1RXFP1KMT2A | |
| SCHEMBL9293746 | 0.88 | ADORA2B (0.64) | ADORA2AADORA2BMAPK1RXFP1KMT2A | |
| SCHEMBL9294688 | 0.88 | ADORA2B (0.64) | ADORA2AADORA2BMAPK1RXFP1KMT2A | |
| SCHEMBL9294484 | 0.88 | ADORA2B (0.64) | ADORA2AADORA2BMAPK1RXFP1KMT2A | |
| SCHEMBL9293797 | 0.88 | ADORA2B (0.64) | ADORA2AADORA2BMAPK1RXFP1KMT2A | |
| SCHEMBL8070549 | 0.88 | ADORA2B (0.64) | ADORA2AADORA2BMAPK1RXFP1KMT2A | |
| SCHEMBL9294300 | 0.85 | PDE4A (0.51) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9293290 | 0.84 | PDE4A (0.55) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288721-A | Substituted epoxyalkyl xanthines | CELL THERAPEUTICS, INC. (US) | 1994-02-22 | — | — | US | disclosed |