Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293746 | 1.00 | ADORA2B (0.64) | ADORA2BRXFP1MAPK1KMT2ALMNA | |
| SCHEMBL9294688 | 1.00 | ADORA2B (0.64) | ADORA2BRXFP1MAPK1KMT2ALMNA | |
| SCHEMBL9293797 | 1.00 | ADORA2B (0.64) | ADORA2BRXFP1MAPK1KMT2ALMNA | |
| SCHEMBL9294484 | 1.00 | ADORA2B (0.64) | ADORA2BRXFP1MAPK1KMT2ALMNA | |
| SCHEMBL9293917 | 0.99 | ADORA2B (0.66) | ADORA2BRXFP1MAPK1KMT2ALMNA | |
| SCHEMBL9294500 | 0.88 | ADORA2A (0.59) | ADORA2BRXFP1MAPK1KMT2AADORA2A | |
| SCHEMBL16121000 | 0.85 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120989 | 0.85 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120982 | 0.85 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120999 | 0.85 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121270-A | N-(EPOXYALKYL)XANTHINE DERIVATIVES WHICH MODULATE CELLULAR RESPONSES TO NOXIOUS, PRO-INFLAMMATORY STIMULI | CELL THERAPEUTICS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| US-5866576-A | COMPOUNDS THAT ACT AS DRUGS ON THE CELLULAR AND BIOCHEMICAL LEVEL TO MODULATE CELLULAR RESPONSES TO NOXIOUS, PRO-INFLAMMATORY STIMULI. | CELL THERAPEUTICS, INC. (US) | 1999-02-02 | — | — | US | disclosed |