Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 4/20 | 0.35 |
| ▸ | LDHB | P07195 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12003383 | 0.86 | KDM4E (0.42) | PTGDR2PAX8CCNB2CDK1CCNB1 | |
| SCHEMBL13741412 | 0.76 | KMT2A (0.41) | PTGDR2CCNA2CDK2MEN1KMT2A | |
| SCHEMBL16387713 | 0.73 | ALKBH3 (0.48) | PAX8MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29850874 | 0.70 | ALDH1A1 (0.44) | PTGDR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL22772166 | 0.70 | ALDH1A1 (0.44) | PTGDR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16857579 | 0.69 | KDM4E (0.40) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| Isuzinaxib SCHEMBL12003400 | 0.69 | CYBB (0.48) | PTGDR2MEN1KMT2AALDH1A1TSHR | |
| Isuzinaxib SCHEMBL30527926 | 0.69 | CYBB (0.48) | PTGDR2MEN1KMT2AALDH1A1TSHR | |
| Isuzinaxib SCHEMBL15610231 | 0.68 | CYBB (0.47) | PTGDR2MEN1KMT2AALDH1A1TSHR | |
| Isuzinaxib SCHEMBL29374779 | 0.68 | CYBB (0.47) | PTGDR2MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292744-A | 1-[pyri(mi)dyl-(2)]-5-hydroxy-pyrazole microbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | claimed |