Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 10/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295013 | 1.00 | AHCY (0.44) | AHCYCYP3A4FGFR1SLC22A6ADORA2A | |
| SCHEMBL9569622 | 0.88 | AHCY (0.44) | AHCYCYP3A4FGFR1SLC22A6ADORA2A | |
| SCHEMBL9569676 | 0.88 | AHCY (0.44) | AHCYCYP3A4FGFR1SLC22A6ADORA2A | |
| SCHEMBL9569653 | 0.88 | AHCY (0.44) | AHCYCYP3A4FGFR1SLC22A6ADORA2A | |
| SCHEMBL9295185 | 0.86 | CYP3A4 (0.41) | AHCYCYP3A4FGFR1ADORA2AADORA1 | |
| SCHEMBL9295198 | 0.86 | CYP3A4 (0.41) | AHCYCYP3A4FGFR1ADORA2AADORA1 | |
| SCHEMBL9294967 | 0.82 | AHCY (0.58) | AHCYCYP3A4FGFR1SLC22A6ADORA2A | |
| SCHEMBL9294953 | 0.82 | AHCY (0.58) | AHCYCYP3A4FGFR1SLC22A6ADORA2A | |
| SCHEMBL9569753 | 0.80 | ADORA2A (0.54) | AHCYCYP3A4FGFR1SLC22A6ADORA2A | |
| SCHEMBL9569750 | 0.80 | ADORA2A (0.54) | AHCYCYP3A4FGFR1SLC22A6ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539487-A1 | ANTIVIRAL PHOSPHONO-ALKEN DERIVATIVES OF PURINES | BEECHAM GROUP PLC (GB) | 1993-05-05 | — | — | EP | claimed |
| WO-1992001698-A1 | ANTIVIRAL PHOSPHONO-ALKEN DERIVATIVES OF PURINES | BEECHAM GROUP PLC (GB) | 1992-02-06 | — | — | WO | claimed |
| US-5356886-A | Treating herpes virus infections | BEECHAM GROUP P.L.C. (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0539487-A1 | ANTIVIRAL PHOSPHONO-ALKEN DERIVATIVES OF PURINES | BEECHAM GROUP PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992001698-A1 | ANTIVIRAL PHOSPHONO-ALKEN DERIVATIVES OF PURINES | BEECHAM GROUP PLC (GB) | 1992-02-06 | — | — | WO | disclosed |