SCHEMBL9295481

CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CCCNC(=N)N)C(=O)NC(C(=O)N1CCCC1C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)N1CCCC1C(=O)N1CCCC1C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(=N)N)C(=O)O)C(C)O)C(C)O

nearest known ligand 0.60

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	NTSR1	P30989	13/20	0.59

▸	NTSR2	O95665	11/20	0.59

▸	SORT1	Q99523	9/20	0.59

▸	OPRD1	P41143	3/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9295491	1.00	NTSR1 (0.59)	NTSR1NTSR2SORT1OPRD1
SCHEMBL31519870	0.88	OPRD1 (0.66)	NTSR1NTSR2SORT1OPRD1
SCHEMBL29457313	0.87	SLC6A2 (0.69)	NTSR1NTSR2SORT1OPRD1
SCHEMBL30906006	0.85	NTSR1 (0.57)	NTSR1NTSR2SORT1
SCHEMBL30581294	0.85	MAPK8 (0.61)	NTSR1NTSR2SORT1
SCHEMBL30581301	0.85	MAPK8 (0.61)	NTSR1NTSR2SORT1
SCHEMBL30581327	0.85	MAPK8 (0.58)	NTSR1NTSR2SORT1
SCHEMBL1421525	0.85	NTSR1 (0.72)	NTSR1NTSR2SORT1OPRD1
SCHEMBL1421598	0.85	NTSR1 (0.72)	NTSR1NTSR2SORT1OPRD1
SCHEMBL1421513	0.85	NTSR1 (0.72)	NTSR1NTSR2SORT1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0567578-A4	—	—	1994-04-27	—	—	EP	claimed
EP-0567578-A1	LAMININ A CHAIN DOMAIN VI POLYPEPTIDES	THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US)	1993-11-03	—	—	EP	claimed
WO-1992012727-A1	LAMININ A CHAIN DOMAIN VI POLYPEPTIDES	REGENTS OF THE UNIVERSITY OF MINNESOTA (US)	1992-08-06	—	—	WO	claimed