Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910867 | 0.82 | BRD4 (0.86) | BRD4ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL3573826 | 0.81 | KMT2A (0.57) | BRD4ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL23931860 | 0.81 | KDM4E (0.55) | BRD4ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL19151120 | 0.80 | BRD4 (0.54) | BRD4ALDH1A1KDM4EMAPTSHMT2 | |
| SCHEMBL31490031 | 0.80 | KDM4E (0.53) | BRD4ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL31082406 | 0.79 | KDM4E (0.52) | BRD4ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL13780123 | 0.79 | RAB9A (0.64) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL26789796 | 0.79 | BRD4 (0.49) | BRD4ALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL27677846 | 0.79 | SHMT2 (0.68) | BRD4ALDH1A1KDM4ESHMT2SMN1; SMN2 | |
| SCHEMBL28000194 | 0.79 | BRD4 (0.50) | BRD4ALDH1A1KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573581-A4 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1 INC (US) | 1994-06-29 | — | — | EP | claimed |
| EP-0573581-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1, Inc. (US) | 1993-12-15 | — | — | EP | claimed |
| WO-1992014453-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1, INC. (US) | 1992-09-03 | — | — | WO | claimed |