Cadaverine Tartrate

Cadaverine Tartrate

SCHEMBL9296176

C[N+](C)(C)CCO.C[N+](C)(C)CCO.O=C([O-])C(O)C(O)C(=O)O.[Cl-]

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 1/20 0.31
CHRM3 known ✓ P20309 1/20 0.31
CYP3A4 P08684 2/20 0.50
SLC5A7 Q9GZV3 1/20 0.50
LMNA P02545 4/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TSHR P16473 3/20 0.40
BLM P54132 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
PMP22 Q01453 1/20 0.40
MAPT P10636 2/20 0.35
SLC22A16 Q86VW1 1/20 0.35
GALR3 O60755 1/20 0.32
CYP2C9 P11712 1/20 0.32
PDE4A P27815 1/20 0.32
ALDH1A1 P00352 1/20 0.32
APEX1 P27695 1/20 0.32
PSMD14 O00487 1/20 0.32
PLA2G1B P04054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cadaverine Tartrate SCHEMBL2586847 0.98 LMNA (0.46) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL188002 0.98 LMNA (0.46) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL9581037 0.98 LMNA (0.46) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL5311459 0.98 LMNA (0.46) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL8167949 0.98 LMNA (0.46) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL28683781 0.96 LMNA (0.44) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL15993811 0.93 LMNA (0.41) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL14856284 0.93 LMNA (0.41) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL21246910 0.92 CYP3A4 (0.59) CYP3A4SLC5A7LMNAMEN1KMT2A
Cadaverine Tartrate SCHEMBL30402903 0.92 LMNA (0.52) CYP3A4SLC5A7LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585349-A4 METHOD AND APPARATUS FOR -i(IN VITRO) FERTILIZATION. SINAI SCHOOL MEDICINE (US) 1994-12-07 EP disclosed
EP-0585349-A1 METHOD AND APPARATUS FOR $i(IN VITRO) FERTILIZATION MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK (US) 1994-03-09 EP disclosed
WO-1992020359-A1 METHOD AND APPARATUS FOR IN VITRO FERTILIZATION MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK (US) 1992-11-26 WO disclosed