Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | VDR | P11473 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323814 | 0.82 | ATM (0.48) | L3MBTL1TDP1ATMALDH1A1CYP4F2 | |
| SCHEMBL3192546 | 0.82 | SRD5A2 (0.58) | ALDH1A1MAPK14CYP4F2CYP4A11LTA4H | |
| SCHEMBL6242055 | 0.81 | NCOA1 (0.51) | L3MBTL1TDP1ATMALDH1A1CYP4F2 | |
| SCHEMBL27305578 | 0.81 | ALDH1A1 (0.48) | L3MBTL1TDP1ATMALDH1A1CYP4F2 | |
| SCHEMBL26637232 | 0.80 | KMT2A (0.49) | L3MBTL1TDP1ATMALDH1A1CYP4F2 | |
| SCHEMBL30657386 | 0.80 | KMT2A (0.49) | L3MBTL1TDP1ATMALDH1A1CYP4F2 | |
| SCHEMBL5204961 | 0.79 | L3MBTL1 (0.51) | L3MBTL1TDP1ATMALDH1A1MAPK1 | |
| SCHEMBL1745415 | 0.79 | FFAR1 (0.64) | MAPK1VDRRXRAFFAR1SMN1; SMN2 | |
| SCHEMBL18301312 | 0.78 | TDP1 (0.59) | L3MBTL1TDP1ATMALDH1A1MAPK1 | |
| SCHEMBL7558146 | 0.78 | KMT2A (0.56) | L3MBTL1TDP1ALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286894-A | Phenyl acrylic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |