Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzyl Benzoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL9956241 | 0.91 | ALDH1A1 (0.64) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| Benzoic Acid SCHEMBL136510 | 0.91 | ALDH1A1 (0.64) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| Benzoic Acid SCHEMBL28388934 | 0.91 | ALDH1A1 (0.64) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| Benzoic Acid SCHEMBL7688676 | 0.91 | ALDH1A1 (0.64) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| Benzyl Benzoate SCHEMBL1142343 | 0.88 | KMT2A (0.77) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL1866116 | 0.87 | ALDH1A1 (0.70) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL1866113 | 0.87 | ALDH1A1 (0.70) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL3391 | 0.87 | ALDH1A1 (0.70) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL2788016 | 0.85 | MAPT (0.58) | KMT2AALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL20515564 | 0.85 | ALDH1A1 (0.68) | KMT2ATDP1SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9050272-B1 | Nail polish composition | HOMMA MICHAEL MITSUO (US) | 2015-06-09 | — | — | US | claimed |
| US-9050272-B1 | Nail polish composition | HOMMA MICHAEL MITSUO (US) | 2015-06-09 | — | — | US | disclosed |
| WO-2013086405-A1 | LONG LASTING FINGERNAIL LACQUER AND METHOD FOR MANUFACTURE | HOMMA MICHAEL MITSUO (US) | 2013-06-13 | — | — | WO | disclosed |
| US-20130149266-A1 | Long lasting fingernail lacquer and method for manufacture | HOMMA MICHAEL MITSUO (US) | 2013-06-13 | — | — | US | disclosed |
| US-5290543-A | Overcoatings for nails | REVLON CONSUMER PRODUCTS CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |