SCHEMBL9296642

SCHEMBL9296642

CC(=NNN)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 5/20 0.47
NOS1 P29475 4/20 0.47
NOS3 P29474 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
BLM P54132 1/20 0.46
MEN1 O00255 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.45
GSR P00390 1/20 0.44
OTC P00480 1/20 0.44
DDAH1 O94760 2/20 0.42
DPP7 Q9UHL4 1/20 0.41
ARG1 P05089 3/20 0.41
ARG2 P78540 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915399 0.84 NOS2 (0.50) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL7172385 0.84 NOS2 (0.50) NOS2NOS1NOS3CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL7218895 0.83 NOS2 (0.51) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL7908791 0.80 NOS2 (0.46) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL7908788 0.80 NOS2 (0.46) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL919222 0.80 KDM4E (0.56) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL236178 0.80 KDM4E (0.56) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL180969 0.80 KDM4E (0.56) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL7911885 0.79 NOS2 (0.49) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL7226879 0.79 NOS2 (0.49) NOS2NOS1NOS3CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582630-A4 N?6 -(HYDRAZINOIMINOMETHYL)LYSINE AND METHOD OF INHIBITING NITRIC OXIDE FORMATION IN BODY CORNELL RES FOUNDATION INC (US) 1994-06-22 EP disclosed
EP-0582630-A1 N?6 -(HYDRAZINOIMINOMETHYL)LYSINE AND METHOD OF INHIBITING NITRIC OXIDE FORMATION IN BODY CORNELL RESEARCH FOUNDATION, INC. (US) 1994-02-16 EP disclosed
WO-1992016666-A1 N6-(HYDRAZINOIMINOMETHYL)LYSINE AND METHOD OF INHIBITING NITRIC OXIDE FORMATION IN BODY CORNELL RESEARCH FOUNDATION, INC. (US) 1992-10-01 WO disclosed