Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157241 | 0.81 | ALOX5 (0.45) | ALDH1A1HSD17B10HIF1ACYP1B1LMNA | |
| SCHEMBL448679 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HIF1ALMNAKDM4E | |
| SCHEMBL83008 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HIF1ALMNAKDM4E | |
| SCHEMBL6241470 | 0.76 | GRIN2D (0.42) | ALDH1A1HSD17B10LMNAGAAKMT2A | |
| SCHEMBL11300299 | 0.76 | ALDH1A1 (0.50) | G6PDCCR6HKDC1ALDH1A1HSD17B10 | |
| SCHEMBL28299482 | 0.73 | ALDH1A1 (0.39) | CCR6ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL190685 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1SMN1; SMN2 | |
| SCHEMBL15063036 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1SMN1; SMN2 | |
| SCHEMBL25966 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1SMN1; SMN2 | |
| SCHEMBL31127473 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300663-A | Contrast formation, light absorption | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5206395-A | Photosensitive contrast agent | CIBA-GEIGY CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |
| US-5177227-A | Photosensitizers, photoinitiators, indicators | CIBA-GEIGY CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |