Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298086 | 0.84 | HDAC6 (0.46) | HDAC6MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL4664006 | 0.76 | NPSR1 (0.44) | HDAC6MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL4523132 | 0.75 | CCNE1 (0.46) | MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10518624 | 0.72 | ALDH1A1 (0.72) | HDAC6MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL2487504 | 0.72 | HCAR2 (0.60) | MAPTALDH1A1RAB9ANPC1GSK3B | |
| SCHEMBL6114196 | 0.72 | GSK3B (0.44) | ALDH1A1GSK3BKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL1358436 | 0.71 | GSK3B (0.47) | HDAC6MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL9298456 | 0.70 | NPSR1 (0.42) | HDAC6MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL21332962 | 0.70 | TSHR (0.43) | MAPTALDH1A1RAB9ANPC1GSK3B | |
| SCHEMBL6096301 | 0.70 | NPSR1 (0.39) | HDAC6MAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371097-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5364871-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0417751-A2 | New thiazole derivatives, processes for the preparation thereof and pharmaceutical compositon comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |