Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ST6GAL1 | P15907 | 8/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109973 | 0.85 | LMNA (0.52) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL9297806 | 0.79 | LMNA (0.52) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27364585 | 0.75 | LMNA (0.61) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL9856687 | 0.75 | LMNA (0.70) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1896533 | 0.75 | LMNA (0.70) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL14178411 | 0.75 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL383499 | 0.75 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL17304691 | 0.75 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL2811458 | 0.75 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL13524621 | 0.75 | LMNA (0.73) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595839-A4 | — | — | 1994-08-03 | — | — | EP | disclosed |
| EP-0595839-A1 | METHOD AND COMPOUNDS FOR RNA SYNTHESIS | THE PERKIN-ELMER CORPORATION (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5281701-A | Process and compounds for RNA synthesis | APPLIED BIOSYSTEMS, INC. (US) | 1994-01-25 | — | — | US | disclosed |
| WO-1993001204-A1 | METHOD AND COMPOUNDS FOR RNA SYNTHESIS | APPLIED BIOSYSTEMS, INC. (US) | 1993-01-21 | — | — | WO | disclosed |