SCHEMBL27364585

SCHEMBL27364585

CC(C)N(C(C)C)P(O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.61
THRB P10828 1/20 0.61
MTOR P42345 1/20 0.61
MDM2 Q00987 1/20 0.61
NCOA1 Q15788 1/20 0.61
NCOA3 Q9Y6Q9 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.57
TSHR P16473 1/20 0.54
GLA P06280 1/20 0.54
ST6GAL1 P15907 8/20 0.51
P2RY2 P41231 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL584613 0.86 LMNA (0.70) LMNATHRBMTORMDM2NCOA1
SCHEMBL8740127 0.85 LMNA (0.66) LMNATHRBMTORMDM2NCOA1
SCHEMBL7026416 0.85 LMNA (0.72) LMNATHRBMTORMDM2NCOA1
SCHEMBL28403435 0.85 LMNA (0.72) LMNATHRBMTORMDM2NCOA1
SCHEMBL338709 0.84 LMNA (0.70) LMNATHRBMTORMDM2NCOA1
SCHEMBL9297806 0.83 LMNA (0.52) LMNATHRBMTORMDM2NCOA1
SCHEMBL17304691 0.82 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL14178411 0.82 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL2811458 0.82 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL18231346 0.82 LMNA (0.73) LMNATHRBMTORMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1084854-A The preparation method of the primer of detection, direct gene somatotype human herpes simplex vicus DNA SHANGHAI NO 2 MILITARY MEDICAL (CN) 1994-04-06 CN disclosed
CN-1071459-A The primer of a pair of detection bow-shaped worm dna and preparation thereof SHANGHAI NO 2 MEDICAL UNIV (CN) 1993-04-28 CN disclosed
CN-1059561-A Two couples of preparation methods that detect the primer of human cytomegalic inclusion disease virus DNA SHANGHAI NO 2 MEDICAL UNIV (CN) 1992-03-18 CN disclosed