Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298914 | 0.79 | MAPK1 (0.32) | ALDH1A1 | |
| SCHEMBL2654367 | 0.70 | ALDH1A1 (0.36) | ALDH1A1NPSR1CYP2C19 | |
| SCHEMBL23341293 | 0.64 | TP53 (0.39) | ALDH1A1TSHR | |
| SCHEMBL11757204 | 0.63 | HTT (0.35) | ALDH1A1NPSR1LMNACYP2C19 | |
| SCHEMBL23145532 | 0.61 | TRPA1 (0.39) | ALDH1A1TSHRCYP2C19 | |
| SCHEMBL23341266 | 0.61 | IDO1 (0.39) | ALDH1A1TSHRCYP2C19 | |
| SCHEMBL2966074 | 0.58 | MEN1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL9784929 | 0.56 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL2668786 | 0.56 | KMT2A (0.36) | ALDH1A1NPSR1TSHR | |
| SCHEMBL5674135 | 0.56 | CYP2C19 (0.39) | ALDH1A1NPSR1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312904-A | Body imaging agents | AMERSHAM INTERNATIONAL PLC (GB) | 1994-05-17 | — | — | US | disclosed |
| EP-0386873-B1 | CATIONIC COMPLEXES OF TECHNETIUM 99M, AND LIGANDS THEREFOR | AMERSHAM INTERNATIONAL plc (GB) | 1993-09-15 | — | — | EP | disclosed |
| EP-0386873-A1 | Cationic complexes of technetium 99m, and ligands therefor | AMERSHAM INTERNATIONAL plc (GB) | 1990-09-12 | — | — | EP | disclosed |