SCHEMBL9299166

SCHEMBL9299166

C=C(C(=O)OC)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
TRPV1 Q8NER1 3/20 0.46
SRD5A2 P31213 1/20 0.46
PTPN1 P18031 2/20 0.45
NR4A1 P22736 1/20 0.45
NR4A2 P43354 1/20 0.45
NR4A3 Q92570 1/20 0.45
GSK3B P49841 2/20 0.44
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
MAOB P27338 1/20 0.43
EPHX2 P34913 1/20 0.43
KDM4E B2RXH2 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
PTGS1 P23219 2/20 0.42
MMP1 P03956 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057415 0.84 ALDH1A1 (0.46) CES2CES1KDM4E
SCHEMBL11461692 0.84 MAPT (0.43) CES2CES1PTPN1KDM4EHTT
SCHEMBL21837346 0.84 HDAC1 (0.53) SRD5A2EPHX2HTTKMT2A
SCHEMBL24534568 0.83 NPC1 (0.49) CES2CES1TRPV1SRD5A2PTPN1
SCHEMBL4224773 0.83 CES2 (0.48) CES2CES1TRPV1SRD5A2PTPN1
SCHEMBL4020790 0.82 CES2 (0.52) CES2
SCHEMBL10441841 0.81 CES2 (0.67) CES2CES1TRPV1SRD5A2PTPN1
SCHEMBL840765 0.81 NPSR1 (0.54) CES2CES1SRD5A2PTPN1GSK3B
SCHEMBL19746355 0.80 NPSR1 (0.57) CES2SRD5A2MAOBHTTKMT2A
SCHEMBL28587857 0.79 CES2 (0.57) CES2CES1TRPV1SRD5A2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115537194-A Ligand modified quantum dot, quantum dot film, preparation method of quantum dot film and light-emitting device TCL科技集团股份有限公司 2022-12-30 CN claimed
US-5352820-A Expedient route to aryl propenoic esters AMERICAN CYANAMID COMPANY 1994-10-04 US claimed
CN-113509961-B Application of chitosan/cellulose composite microsphere immobilized copper in preparation of allylsilane compound 湖北工程学院 2023-05-23 CN disclosed
CN-115537194-A Ligand modified quantum dot, quantum dot film, preparation method of quantum dot film and light-emitting device TCL科技集团股份有限公司 2022-12-30 CN disclosed
US-5352820-A Expedient route to aryl propenoic esters AMERICAN CYANAMID COMPANY 1994-10-04 US disclosed