Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299707 | 0.72 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL9298020 | 0.70 | CYP3A4 (0.41) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL9299038 | 0.69 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL9299144 | 0.62 | ALDH1A1 (0.33) | — | |
| SCHEMBL9298906 | 0.61 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL10920937 | 0.57 | CYP2D6 (0.55) | CYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL7057716 | 0.57 | CARM1 (0.51) | CYP3A4 | |
| SCHEMBL17346134 | 0.56 | MAPT (0.57) | — | |
| SCHEMBL23569534 | 0.56 | TSHR (0.45) | — | |
| SCHEMBL5680420 | 0.56 | CYP2D6 (0.63) | CYP1A2CYP3A4CYP2D6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312904-A | Body imaging agents | AMERSHAM INTERNATIONAL PLC (GB) | 1994-05-17 | — | — | US | disclosed |
| EP-0386873-B1 | CATIONIC COMPLEXES OF TECHNETIUM 99M, AND LIGANDS THEREFOR | AMERSHAM INTERNATIONAL plc (GB) | 1993-09-15 | — | — | EP | disclosed |
| EP-0386873-A1 | Cationic complexes of technetium 99m, and ligands therefor | AMERSHAM INTERNATIONAL plc (GB) | 1990-09-12 | — | — | EP | disclosed |