Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.70 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.61 |
| ▸ | MC5R | P33032 | 1/20 | 0.61 |
| ▸ | MC3R | P41968 | 1/20 | 0.61 |
| ▸ | MC1R | Q01726 | 1/20 | 0.61 |
| ▸ | G6PD | P11413 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD5 | P21918 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543272 | 0.86 | HTR2A (0.94) | HTR2AHTR1ABCHEHTTKDM4E | |
| SCHEMBL733629 | 0.86 | HTR2A (0.94) | HTR2AHTR1ABCHEHTTKDM4E | |
| SCHEMBL734226 | 0.84 | HTR2A (0.91) | HTR2AHTR1AHRH3BCHEHTT | |
| SCHEMBL32669458 | 0.84 | HTR2A (0.91) | HTR2AHTR1AHRH3BCHEHTT | |
| SCHEMBL17232881 | 0.84 | MC5R (0.83) | HTR2AHTR1AMC5RMC3RMC1R | |
| SCHEMBL2259204 | 0.83 | HTR1A (0.88) | HTR2AHTR1AHTTKDM4ELMNA | |
| SCHEMBL25295661 | 0.83 | HTR2A (1.00) | HTR2AHTR1ABCHEHTTKDM4E | |
| SCHEMBL7970552 | 0.82 | MC5R (0.81) | HTR2AHTR1AMC5RMC3RMC1R | |
| SCHEMBL5170230 | 0.82 | HTR1A (0.81) | HTR2AHTR1AHTTKDM4ELMNA | |
| SCHEMBL2420293 | 0.82 | HTR1A (0.86) | HTR2AHTR1AHTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623138-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | UNION PHARMA SCIENT APPL (FR) | 1994-11-09 | — | — | EP | disclosed |