Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.36 |
| ▸ | FDPS | P14324 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297600 | 0.91 | FDPS (0.30) | FDPS | |
| SCHEMBL10011526 | 0.72 | CYP3A4 (0.38) | ATM | |
| SCHEMBL9299592 | 0.72 | — | — | |
| SCHEMBL27628722 | 0.71 | TSHR (0.38) | GGPS1SMPD1FDPSMEN1MAPT | |
| SCHEMBL28222322 | 0.71 | TSHR (0.38) | GGPS1SMPD1FDPSMEN1MAPT | |
| SCHEMBL27628572 | 0.71 | TSHR (0.38) | GGPS1SMPD1FDPSMEN1MAPT | |
| SCHEMBL23579190 | 0.70 | TSHR (0.42) | GGPS1SMPD1FDPSMEN1MAPT | |
| SCHEMBL11841268 | 0.70 | CES2 (0.45) | GGPS1SMPD1FDPSCES2LPAR1 | |
| SCHEMBL9325518 | 0.70 | GGPS1 (0.43) | GGPS1SMPD1FDPSCES2LPAR1 | |
| SCHEMBL8846370 | 0.70 | TSHR (0.42) | GGPS1SMPD1FDPSMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298663-A | Process for the preparation of protected phosphine oxides | CIBA-GEIGY CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0501702-A2 | Process for the preparation of protected phosphine oxides | CIBA-GEIGY AG (CH) | 1992-09-02 | — | — | EP | disclosed |