Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4996530 | 0.80 | CA1 (0.40) | CA1CA2CA9CA12CA4 | |
| SCHEMBL4167404 | 0.80 | CA1 (0.40) | CA1CA2CA9CA12CA4 | |
| SCHEMBL8872590 | 0.79 | CA1 (0.57) | CA1CA2CA9CA12CA4 | |
| SCHEMBL10873960 | 0.79 | CA1 (0.57) | CA1CA2CA9CA12CA4 | |
| SCHEMBL16768963 | 0.79 | CA1 (0.57) | CA1CA2CA9CA12CA4 | |
| SCHEMBL7145333 | 0.78 | CA2 (0.45) | CA1CA2CA9CA12CA4 | |
| SCHEMBL4205268 | 0.77 | YWHAZ (0.36) | CA1CA2CA9 | |
| SCHEMBL13909435 | 0.77 | YWHAZ (0.36) | CA1CA2CA9 | |
| SCHEMBL9298111 | 0.77 | CA1 (0.38) | CA1CA2CA9CA12CA4 | |
| SCHEMBL8836026 | 0.77 | CA2 (0.47) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003185-A1 | DISUBSTITUTED AND DEOXY DISUBSTITUTED DERIVATIVES OF α-D-MANNOFURANOSIDES AND β-L-GULOFURANOSIDES HAVING ANTI-INFLAMMATORY AND ANTI-PROLIFERATIVE ACTIVITY | MEDICARB INC. (US) | 1994-02-17 | — | — | WO | claimed |
| US-5360794-A | Disubstituted and deoxy disubstituted derivatives of α-D-mannofuranosides and β-L-gulofuranosides having anti-inflammatory and anti-proliferative activity | MEDICARB INC. (US) | 1994-11-01 | — | — | US | disclosed |