Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NAT1 | P18440 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525052 | 1.00 | EGFR (0.63) | EGFRALDH1A1GAAMAPTKDM4E | |
| SCHEMBL30825519 | 1.00 | EGFR (0.63) | EGFRALDH1A1GAAMAPTKDM4E | |
| SCHEMBL1525054 | 1.00 | EGFR (0.63) | EGFRALDH1A1GAAMAPTKDM4E | |
| SCHEMBL3438149 | 0.97 | EGFR (0.59) | EGFRALDH1A1GAAMAPTKDM4E | |
| SCHEMBL3438150 | 0.97 | EGFR (0.59) | EGFRALDH1A1GAAMAPTKDM4E | |
| SCHEMBL16745481 | 0.89 | EGFR (0.77) | EGFRALDH1A1GAAMAPTKDM4E | |
| SCHEMBL1524403 | 0.86 | CRHBP (0.61) | EGFRALDH1A1GAAMAPTNFE2L2 | |
| SCHEMBL1524404 | 0.86 | CRHBP (0.61) | EGFRALDH1A1GAAMAPTNFE2L2 | |
| SCHEMBL28009931 | 0.86 | MAPT (0.51) | EGFRALDH1A1GAAMAPTKDM4E | |
| SCHEMBL3438405 | 0.83 | RAB9A (0.61) | EGFRALDH1A1GAAMAPTNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117701516-A | Alkene reductase, enzyme preparation, nucleic acid, expression vector, preparation method and application | 河北工业大学 | 2024-03-15 | — | — | CN | disclosed |
| US-5281622-A | Administering to mammals as antiinflammatory agent | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1994-01-25 | — | — | US | disclosed |
| US-5250735-A | Antitumor or antiinflammatory agents, analgesics | UNIVERSITY OF PITTSBURGH (US) | 1993-10-05 | — | — | US | disclosed |