Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299952 | 0.81 | KCNMA1 (0.41) | KAT2BTDP1TSHRKMT2AMAPT | |
| SCHEMBL9387736 | 0.78 | KAT2B (0.52) | KAT2BALDH1A1TDP1TSHRHPGD | |
| SCHEMBL16831368 | 0.75 | KAT2B (0.58) | KAT2BALDH1A1TDP1TSHRHPGD | |
| SCHEMBL9301043 | 0.74 | KAT2B (0.35) | KAT2BALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL9300400 | 0.72 | NPSR1 (0.43) | KAT2BTDP1KMT2AMAPTMEN1 | |
| SCHEMBL16831412 | 0.72 | KAT2B (0.64) | KAT2BALDH1A1TDP1TSHRHPGD | |
| SCHEMBL29901090 | 0.71 | KAT2B (0.60) | KAT2BALDH1A1TDP1TSHRHPGD | |
| SCHEMBL9299967 | 0.71 | MAPT (0.46) | KAT2BALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL9300395 | 0.71 | ATM (0.39) | KAT2BALDH1A1TDP1KMT2AMAPT | |
| SCHEMBL27940262 | 0.71 | ALDH1A1 (0.64) | KAT2BALDH1A1TDP1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362747-A | Promoters, inhibitors | ABBOTT LABORATORIES (US) | 1994-11-08 | — | — | US | disclosed |
| WO-1994012163-A1 | 2-NITROARYL AND 2-CYANOARYL COMPOUNDS AS REGULATORS OF NITRIC OXIDE SYNTHASE | ABBOTT LABORATORIES (US) | 1994-06-09 | — | — | WO | disclosed |