Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300305 | 0.91 | ALOX5 (0.59) | ALOX5P2RY14 | |
| SCHEMBL9301392 | 0.91 | ALOX5 (0.58) | ALOX5P2RY14 | |
| SCHEMBL9301050 | 0.90 | ALOX5 (0.60) | ALOX5P2RY14 | |
| SCHEMBL9303401 | 0.89 | ALOX5 (0.52) | ALOX5P2RY14 | |
| SCHEMBL9301964 | 0.89 | ALOX5 (0.49) | ALOX5P2RY14 | |
| SCHEMBL9301054 | 0.87 | ALOX5 (0.50) | ALOX5P2RY14 | |
| SCHEMBL9301469 | 0.86 | ALOX5 (0.47) | ALOX5P2RY14 | |
| SCHEMBL9382166 | 0.85 | ALOX5 (0.61) | ALOX5P2RY14 | |
| SCHEMBL9301698 | 0.85 | ALOX5 (0.61) | ALOX5P2RY14 | |
| SCHEMBL9302530 | 0.85 | P2RY14 (0.63) | ALOX5P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308852-A | Cardiovascular disorders | MERCK FROSST CANADA, INC. (CA) | 1994-05-03 | — | — | US | disclosed |
| EP-0579304-A1 | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1994-01-19 | — | — | EP | disclosed |
| WO-1994000444-A1 | HETEROARYLNAPHTHALENES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1994-01-06 | — | — | WO | disclosed |