Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382166 | 0.93 | ALOX5 (0.61) | P2RY14ALOX5 | |
| SCHEMBL9300867 | 0.92 | ALOX5 (0.62) | P2RY14ALOX5MRGPRX4 | |
| SCHEMBL9301164 | 0.89 | P2RY14 (0.49) | P2RY14ALOX5 | |
| SCHEMBL9301392 | 0.89 | ALOX5 (0.58) | P2RY14ALOX5 | |
| SCHEMBL9301469 | 0.88 | ALOX5 (0.47) | P2RY14ALOX5 | |
| SCHEMBL9303401 | 0.87 | ALOX5 (0.52) | P2RY14ALOX5 | |
| SCHEMBL9300305 | 0.87 | ALOX5 (0.59) | P2RY14ALOX5 | |
| SCHEMBL9301050 | 0.86 | ALOX5 (0.60) | P2RY14ALOX5 | |
| SCHEMBL9301503 | 0.86 | ALOX5 (0.60) | P2RY14ALOX5 | |
| SCHEMBL9300801 | 0.85 | ALOX5 (0.49) | P2RY14ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308852-A | Cardiovascular disorders | MERCK FROSST CANADA, INC. (CA) | 1994-05-03 | — | — | US | disclosed |
| EP-0579304-A1 | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1994-01-19 | — | — | EP | disclosed |
| WO-1994000444-A1 | HETEROARYLNAPHTHALENES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1994-01-06 | — | — | WO | disclosed |