Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | RHEB | Q15382 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300868 | 0.87 | GPR84 (0.49) | SLC22A6NR4A2GPR84ALDH1A1F7 | |
| Indoxyl Sulfate SCHEMBL9743592 | 0.77 | SLC22A6 (1.00) | SLC22A6NR4A2GPR84ALDH1A1 | |
| Indoxyl Sulfate SCHEMBL15755 | 0.77 | SLC22A6 (1.00) | SLC22A6NR4A2GPR84ALDH1A1 | |
| Indoxyl Sulfate SCHEMBL29377051 | 0.77 | SLC22A6 (1.00) | SLC22A6NR4A2GPR84ALDH1A1 | |
| SCHEMBL29051233 | 0.76 | GPR84 (0.55) | NR4A2GPR84ALDH1A1F7F3 | |
| SCHEMBL6930062 | 0.76 | SLC22A6 (0.51) | SLC22A6SLC6A4 | |
| SCHEMBL21596979 | 0.76 | GPR84 (0.50) | NR4A2GPR84ALDH1A1F7F3 | |
| Sulfuric Acid SCHEMBL22441041 | 0.76 | GPR84 (0.54) | NR4A2GPR84ALDH1A1F7F3 | |
| SCHEMBL305772 | 0.75 | NR4A2 (0.49) | NR4A2GPR84ALDH1A1F7F3 | |
| SCHEMBL1614860 | 0.75 | SLC22A6 (0.62) | SLC22A6NR4A2GPR84ALDH1A1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364767-A | 6-chloroindole derivatives; colorimetric and quantitative analysis | RESEARCH ORGANICS, IN. (US) | 1994-11-15 | — | — | US | claimed |
| US-5364767-A | 6-chloroindole derivatives; colorimetric and quantitative analysis | RESEARCH ORGANICS, IN. (US) | 1994-11-15 | — | — | US | disclosed |