Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451659 | 0.81 | ACE (0.55) | PPARGPPARAPPARDACE | |
| SCHEMBL6577809 | 0.80 | PPARA (0.48) | PPARGPPARAPPARDACE | |
| SCHEMBL8449806 | 0.80 | ACE (0.56) | PPARGPPARAPPARDACEKMT2A | |
| SCHEMBL8450399 | 0.79 | PPARG (0.48) | PPARGPPARAPPARDACE | |
| SCHEMBL6576098 | 0.79 | ACE (0.48) | PPARGPPARAPPARDACE | |
| SCHEMBL11331809 | 0.78 | GPR139 (0.45) | GPR139PPARGPPARAPPARDACE | |
| SCHEMBL8452692 | 0.76 | PPARA (0.51) | PPARGPPARAPPARDACEMME | |
| SCHEMBL8447586 | 0.75 | ACE (0.46) | PPARGPPARAPPARDACEKMT2A | |
| SCHEMBL4954825 | 0.74 | FNTA (0.54) | PPARGPPARAACEFNTAFNTB | |
| SCHEMBL11331818 | 0.74 | ACE (0.43) | GPR139PPARGPPARAPPARDACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292926-A | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0326326-B1 | CYSTEINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| EP-0326326-A1 | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |