Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.36 |
| ▸ | JAK2 | O60674 | 6/20 | 0.36 |
| ▸ | JAK1 | P23458 | 6/20 | 0.36 |
| ▸ | TYK2 | P29597 | 6/20 | 0.36 |
| ▸ | JAK3 | P52333 | 6/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6284497 | 0.69 | SMPD3 (0.37) | — | |
| SCHEMBL9299545 | 0.64 | JAK2 (0.38) | IRAK4JAK2JAK1TYK2JAK3 | |
| SCHEMBL29759466 | 0.64 | IRAK4 (0.38) | IRAK4JAK2JAK1TYK2JAK3 | |
| SCHEMBL1693499 | 0.64 | EPHB3 (0.51) | IRAK4JAK2JAK1TYK2JAK3 | |
| SCHEMBL11300658 | 0.64 | EPHB3 (0.55) | JAK2JAK1TYK2JAK3RIPK2 | |
| Hydrochloric Acid SCHEMBL30566533 | 0.63 | IRAK4 (0.37) | IRAK4JAK2JAK1TYK2JAK3 | |
| SCHEMBL946897 | 0.63 | IRAK4 (0.68) | IRAK4 | |
| SCHEMBL17632551 | 0.62 | TGFBR1 (0.50) | JAK2JAK1TYK2JAK3RIPK2 | |
| SCHEMBL12699179 | 0.62 | JAK2 (0.56) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL21285357 | 0.62 | JAK2 (0.47) | JAK2JAK1TYK2JAK3TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302712-A | Intermediates for cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| US-5215982-A | Antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0427248-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |