Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.64 |
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARA | Q07869 | 7/20 | 0.63 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301567 | 0.91 | ACE (0.52) | ACEPPARGPPARAPPARD | |
| SCHEMBL9302390 | 0.89 | ACE (0.51) | ACEPPARGPPARAPPARD | |
| SCHEMBL11516592 | 0.86 | ACE (0.60) | ACEPPARGPPARAPPARD | |
| SCHEMBL4566374 | 0.84 | ACE (0.70) | ACEPPARGPPARAPPARD | |
| SCHEMBL4566373 | 0.84 | ACE (0.70) | ACEPPARGPPARAPPARD | |
| SCHEMBL1278179 | 0.82 | PPARA (0.89) | ACEPPARGPPARAPPARD | |
| SCHEMBL11331399 | 0.82 | PPARA (0.89) | ACEPPARGPPARAPPARD | |
| SCHEMBL1278177 | 0.82 | PPARA (0.89) | ACEPPARGPPARAPPARD | |
| SCHEMBL1632958 | 0.81 | ACE (0.66) | ACEPPARGPPARAPPARD | |
| SCHEMBL28344059 | 0.80 | ACE (0.68) | ACEPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292926-A | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0326326-A1 | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |