Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301035 | 0.91 | ACE (0.64) | ACEPPARGPPARAPPARD | |
| SCHEMBL9302390 | 0.89 | ACE (0.51) | ACEPPARGPPARAGAAALDH1A1 | |
| SCHEMBL1277840 | 0.82 | PPARG (0.74) | ACEPPARGPPARAALDH1A1CACNA1B | |
| SCHEMBL3031211 | 0.82 | PPARG (0.74) | ACEPPARGPPARAALDH1A1CACNA1B | |
| SCHEMBL1277844 | 0.82 | PPARG (0.74) | ACEPPARGPPARAALDH1A1CACNA1B | |
| SCHEMBL1634040 | 0.81 | ACE (0.56) | ACEPPARGPPARAGAAALDH1A1 | |
| SCHEMBL2909471 | 0.78 | PPARA (0.53) | ACEPPARGPPARAGAACACNA1B | |
| SCHEMBL9727304 | 0.76 | PPARG (0.72) | ACEPPARGPPARAALDH1A1CACNA1B | |
| SCHEMBL11516592 | 0.76 | ACE (0.60) | ACEPPARGPPARAPPARD | |
| SCHEMBL27360388 | 0.75 | HTT (0.47) | GAAALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292926-A | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0326326-A1 | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |